GNA12.html

Guanine nucleotide binding protein (G protein) alpha 12

PDB rendering based on 1zca.

Available structures: 1zca

Identifiers

Symbols

GNA12; RMP; MGC104623; MGC99644; NNX3; gep

External IDs

Gene ontology
Molecular function:	• nucleotide binding • GTPase activity • signal transducer activity • protein binding • GTP binding • guanyl nucleotide binding
Cellular component:	• membrane
Biological process:	• in utero embryonic development • signal transduction • G-protein coupled receptor protein signaling pathway • protein kinase cascade • Rho protein signal transduction • blood coagulation • regulation of cell shape • cell differentiation • embryonic digit morphogenesis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_007353 (mRNA)
NP_031379 (protein)

Location

Pubmed search

Guanine nucleotide binding protein (G protein) alpha 12, also known as GNA12, is a human gene.¹

References

This article on a gene on chromosome 7 is a stub. You can help Wikipedia by expanding it.

v • d • e Acid anhydride hydrolases: GTPases/G proteins (EC 3.6.5)

3.6.5.1: Heterotrimeric G protein	G_αs - G_αi (GNAI1, GNAI2, GNAI3) - G_αq/11 (GNAQ, GNA11) - G_α12/13 (GNA12, GNA13) - Transducin (GNAT1, GNAT2)

3.6.5.2: Small GTPase > Ras superfamily	Ras - Rab (Rab27) - Arf (Arf6) - Ran - Rheb - Rho family (RhoA, RhoB, CDC42, Rac1) - Rap

3.6.5.3: Elongation factor	Prokaryotic (EF-Tu, EF-Ts, EF-G) - Eukaryotic

3.6.5.5-6: Other	Dynamin (is a GTPase, is not a G protein) - Tubulin

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