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Icaridin
Picaridin
IUPAC name 1-piperidinecarboxylic acid

2-(2-hydroxyethyl)-1-­methylpropylester
PubChem 125098
Identifiers
CAS number 119515-38-7
SMILES
 
Properties
Molecular formula C12H23NO3
Molar mass 229.3 g/mol
Boiling point

296 °C
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox references

Icaridin, also known as picaridine, KBR 3023, under the INCI name hydroxyethyl isobutyl piperidine carboxylate, and under the old trade name Bayrepel and the current trade name Saltidin, is an insect repellent. It has a broad efficacy against different insects and is almost colorless and odorless.

The name picaridin was proposed as an International Nonproprietary Name (INN) to the World Health Organization (WHO), but the official name that has been approved by the WHO is icaridin. The compound was developed by the German chemical company Bayer and was given the name Bayrepel. In 2005, LANXESS AG, and its subsidiary Saltigo GmbH were spun-off of Bayer 1 and the compounds was renamed Saltidin in 2008 2.

Contents

Empirical findings

Icaridin has been reported to be as effective as DEET without the irritation associated with DEET.3 According to the WHO, icaridin “demonstrates excellent repellent properties comparable to, and often superior to, those of the standard DEET.” In the United States, the Centers for Disease Control and Prevention recommends using repellants based on icaridin, DEET, or oil of lemon eucalyptus (which may require more applications4), for effective protection against mosquitoes that carry the West Nile virus, Eastern Equine Encephalitis and other illnesses.

Unlike DEET, icaridin does not dissolve plastics.5

Chemistry

The INCI name for icaridin is hydroxyethyl isobutyl piperidine carboxylate6. This chemical name name is wrong as icaridin it is an sec-butyl ester, not an isobutyl ester. Icaridin contains the substructure R2N-C(=O)-O-R, formally making it a substituted carbamate.

See also

References

  1. ^ Bayer completes spin off of Lanxess AG
  2. ^ C&EN News: Saltigo renames insect repellant
  3. ^ Journal of Drugs and Dermatology (Jan-Feb 2004)
  4. ^ CDC Approves New Weapons Against West Nile Virus. WCVB TV, 3 May 2005.
  5. ^ Picaridin
  6. ^ WHO Specifications and evaluations for public health pesticides: Icaridin

External links
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