In medicine, a nodule refers to a relatively hard, roughly spherical abnormal structure. The term is used often in dermatology, where it is used to describe a lesion which can be felt as a bump under the skin. In contrast to plaques and papules, nodules appear to have a depth of structure beneath the surface.
Nodules may form on tendons and muscles in response to injury. The vocal cords may also develop nodules. Nodules are normally benign and often painless, although they can affect the functioning of the organ.
Furuncles and Kaposi's sarcomae are known to cause dermatological nodules.
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