Phosphoinositol.html



Inositol

Phosphate group

Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:

• inositol monophosphate
• inositol trisphosphate
• inositol pentakisphosphate
• inositol hexaphosphate

Functions

Inositol triphosphate

Main article: Inositol triphosphate

Inositol trisphosphate act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans

Other

Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression¹ and Steger² (both in Science Magazine).

References

1. ^ Shen X, et al. Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates. Science. 2003 Jan 3;299(5603):112-4. PMID 12434013
2. ^ Steger DJ, et al. Regulation of chromatin remodeling by inositol polyphosphates. Science. 2003 Jan 3;299(5603):114-6. PMID 12434012

External links

• An Image of Inositol
• MeSH Inositol+Phosphates

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