Tre recombinase.html

Tre recombinase is an experimental enzyme that in lab tests has successfully removed DNA inserted by HIV from infected cells¹. The enzyme was derived from Cre recombinase through selective mutation for the purposes of identifying HIV markers, which are not bounded by loxP sites and therefore disallow attempts at Cre-Lox recombination.

References

^ Sarkar, I. et al. (2007): HIV-1 proviral DNA excision using an evolved recombinase. In: Science. Bd. 316, S. 1912-1915. PMID 17600219 doi:10.1126/science.1141453

External links

Antivirals used against HIV (HAART) (primarily J05)

Reverse transcriptase
inhibitors (RTIs)

Nucleoside & Nucleotide (NRTI)	Nucleoside analogues/NARTIs: Abacavir (ABC)°^§ · Emtricitabine (FTC)°^§ · Lamivudine (3TC)°^§ · Didanosine (ddI)^§ · Zidovudine (AZT)^§ · Apricitabine^† · Stampidine^† · Elvucitabine^† · Racivir^† · Amdoxovir^† · Stavudine (d4T)^§ · Zalcitabine (ddC)^‡ Nucleotide analogues/NtRTIs: Tenofovir°^§

Non-Nucleoside (NNRTI)	Efavirenz°^§ · Nevirapine^§ · diarylpyrimidines (Etravirine, Rilpivirine)^† · Loviride^‡ · Delavirdine^‡ ·

Protease Inhibitors (PI)

Atazanavir° · Fosamprenavir° · Lopinavir°^§ · Darunavir · Nelfinavir^§ · Ritonavir^§ · Saquinavir^§ · Tipranavir · Amprenavir^‡ · Indinavir^‡^§

Entry/fusion inhibitors

Enfuvirtide · Maraviroc · Vicriviroc^† · PRO 140^† · Ibalizumab^†

Integrase inhibitors

Raltegravir · Elvitegravir^†

Maturation inhibitors

Bevirimat^† · Vivecon^†

Combined formulations

Combivir · Atripla · Trizivir · Truvada · Kaletra · Epzicom

Other &
experimental agents

Abzyme · Calanolide A · Ceragenin · Cyanovirin-N · Diarylpyrimidines · Epigallocatechin gallate (EGCG) · Foscarnet · Globoidnan A · Griffithsin · Hydroxyurea · Miltefosine · Portmanteau inhibitors · Seliciclib^† · Synergistic enhancers · Tre recombinase · Zinc finger protein transcription factor · KP-1461^†

Failed
experimental agents

Dexelvucitabine · Capravirine · Emivirine · Lodenosine · Ateviridine · Quinotaline · Brecanavir · Aplaviroc

°DHHS preferred first-line agent. ^†Undergoing clinical trials, not FDA approved. ^‡Formerly or rarely used agent. ^§WHO-EM

This genetics article is a stub. You can help Wikipedia by expanding it.

www.borson.pl • a • Szkolne lata • HTS • Gazeta • Języki obce • Konie • Kawy • obrazy • teksty piosenek r • Jka obsugiwać Kalkulator kredytowy ? Kalkulator kredytowy ? to proste! • Lodz • Torun • Kalisz • Telefon All Right Reserved © 2007, Designed by Stylish Blog.