VMAT1.html

 
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solute carrier family 18 (vesicular monoamine), member 1
Identifiers
Symbol SLC18A1
Alt. Symbols VMAT1, VAT1
Entrez 6570
HUGO 10934
OMIM 193002
RefSeq NM_003053
UniProt P54219
Other data
Locus Chr. 8 p21.3

VMAT1 (Vesicular monoamine transporter 1) is a protein that transports the monoamine neurotransmitters into synaptic vesicles.

In chromaffin cells, it is responsible for transporting newly synthesized epinephrine from the cytosol back into chromaffin granules in preparation for release.

For norepinephrine to be acted upon by PNMT in the cytosol, it must first be shipped out of granules of the chromaffin cells. This may occur via the catecholamine-H+ exchanger VMAT1.

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